north pole, no offence but it sort of sounded like marriage between two certificates rather than two hearts. मन मिले पछि कुरा मिलि हालिन्छ नि | But anyway, it seems you are little confused and worried about if your would-be wife could blend here easily in this culture. Why not?? 
If all these uneducated and illiterate mexicans can settle up, why not your would-be wife? I'm not comparing her to them but just saying you know, we human are adaptive in nature and we adapt quick.
Some of the basic things you would suggest her is:
-to learn American English (I know there are American Language Centers out there, don't send her to ऐरे -गैरे so-called english institutes )
-to learn driving (optional)
-to learn some computer skill (a must)
-more (I leave it to other sajha members)

and btw, I've seen many nepalese compatriots who were very well-known and had honored profession back home, working here in gas station and samosa pasal in their early years, something like that. US companies don't really recognize what skillsets you've earned back homeland. They only honor credentials you've earned in this country, not other country. I'm talking real life stuffs. If you are student,things are little different that what I just wrote in above lines. 

Did you know, even if you go and marry her in Nepal, possibly there is another 5-6 years to bring her up?? So, go , chillax and enjoy your life and have fun and bring some memorable moment. Don't try to sound you are marrying 'certificate' but person. I chuckled a bit as I was going through your words., best.