Your spouse will wait a long time if you apply for AOS based on marriage to a green card holder.  Why not apply for your citizenship and fast track the whole process? 

Just to add:
Yes you can apply as long as she is in status. 
http://www.uscis.gov/portal/site/uscis/menuitem.eb1d4c2a3e5b9ac89243c6a7543f6d1a/?vgnextoid=75783e4d77d73210VgnVCM100000082ca60aRCRD&vgnextchannel=75783e4d77d73210VgnVCM100000082ca60aRCRD