Posted by: eternalsunshine April 5, 2011
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ok here's the thing
mutation is random. you cannot induce a specific mutation at a site. if you could do that then BAM there a nobel prize for you. unfortunately you can only induce random mutations and select for the one that interests you.
secondly, i love the principle of darwin, how?-we are the progeny that have been selected for several thousand years. dont you love when someone says that. you are special. now the real question is how have we evolved. if you ask darwin he might have a different angle of seeing the same thing as todays molecular biologist see. the point is we are selected as a random event of mutations. when you were concieved, there were around 1 mils of your borthers and sisters who competed with you, but what made you so special that you won the race. i dont know the right answer but my guess is you must have inhereted a special mutation that enabled you to swim faster than your borthers and so you are here. the point is mutation is random and in that milion only 1 or may be few survive. this environment is a real killer. if you cant change to suite you have to die. thats the pressure of selection. you were selected.
if you have read immunology text book, there's context that can explain what is a selection pressure and how will a cell be selected or eliminated. its the reaction in the germinal center in which a B cell has to be selected. the out come of this process is that your body will produce more reactive antibody producing B cells. how does it do that? well my fren it a job of a cellular protein that induces random hypermutations. now when new progenies are produced, they will be selected. any one with has strong reactivity will be allowed to survive and one with less or no reactivity will be eliminated. the one which survived will reproduce in a clonal manner and produce more of its kind.
the idea is mutations are random but there a selecting force called mother nature.
@stiffler, i dont know how have you emersed yourseld in science. but science works with "my theory". i wouldn't always believe in the existing data.
mutation is random. you cannot induce a specific mutation at a site. if you could do that then BAM there a nobel prize for you. unfortunately you can only induce random mutations and select for the one that interests you.
secondly, i love the principle of darwin, how?-we are the progeny that have been selected for several thousand years. dont you love when someone says that. you are special. now the real question is how have we evolved. if you ask darwin he might have a different angle of seeing the same thing as todays molecular biologist see. the point is we are selected as a random event of mutations. when you were concieved, there were around 1 mils of your borthers and sisters who competed with you, but what made you so special that you won the race. i dont know the right answer but my guess is you must have inhereted a special mutation that enabled you to swim faster than your borthers and so you are here. the point is mutation is random and in that milion only 1 or may be few survive. this environment is a real killer. if you cant change to suite you have to die. thats the pressure of selection. you were selected.
if you have read immunology text book, there's context that can explain what is a selection pressure and how will a cell be selected or eliminated. its the reaction in the germinal center in which a B cell has to be selected. the out come of this process is that your body will produce more reactive antibody producing B cells. how does it do that? well my fren it a job of a cellular protein that induces random hypermutations. now when new progenies are produced, they will be selected. any one with has strong reactivity will be allowed to survive and one with less or no reactivity will be eliminated. the one which survived will reproduce in a clonal manner and produce more of its kind.
the idea is mutations are random but there a selecting force called mother nature.
@stiffler, i dont know how have you emersed yourseld in science. but science works with "my theory". i wouldn't always believe in the existing data.