Yes you can change your job without hampering your wife's status. As a matter of fact you dont even have to have your I-1485 approved to change the job. The '180 days portability rule' allows you to change your job if your I-485 application has been pending with USCIS for 180 days or more. BTW, are you through the name check already? Anyways, congratualtions on getting a GC !!