It depends on the nature of RFE. If they have asked for expert opinion on education, get expert opinion evaluation. If they have mentioned that the position mentioned is not a specialty occupation, explain it according to the O*Net and Occupational handbook Rule. If they say that the position does not necessarily require a bachelors degree, show them evidences of advertisement in the industry that other employers have sought bachelor degree for the similar position. If they have mentioned that the company/sponsor's information if frivolous or inadequate, provide them with copies of tax returns, photographs, audtied statement, wage reports, W-2, 941s, incorporation documents, Tax Id etc. If you could specify the RFE here, I could answer them accordingly.